Dellegra Combination Tablets  "LTLPharma"100Tablets To Allergic Rhinitis Medication From Japan
 
Contents 
It is a combination drug of fexofenadine (Allegra), a second-generation antihistamine, and pseudoephedrine, an alpha-sympathomimetic agent. The combination of pseudoephedrine enhances the effect on nasal obstruction, and one drug can cover the three major symptoms of allergic rhinitis. It is relatively fast-acting and takes effect shortly after administration. 
Fexofenadine, an antihistamine, is less fat-soluble and less likely to enter the brain, resulting in fewer side effects of drowsiness. In fact, in psychomotor performance tests using a car driving simulator and a word processing test, there was no difference between fexofenadine and placebo. Therefore, there are no restrictions regarding drowsiness, including driving. 
Pseudoephedrine, an alpha sympathomimetic, is a relatively safe drug with less cardiovascular effects than ephedrine, a similar drug. It has been shown to be as effective as or more effective than antileukotriene drugs (Singulair and Kipres) for nasal obstruction. Although it has been used worldwide for some time, this is the first drug to be approved as an ethical drug in Japan. 
 
Efficacy 
Fexofenadine hydrochloride has antagonistic action on H1 receptors and suppressive action on releasing of various chemical mediators. Pseudoephedrine hydrochloride decreases blood flow of nasal mucosa and shows effective improvement on nasal congestion. It improves symptoms of sneezing, runny nose and nasal congestion associated with seasonal allergic rhinitis such as cedar pollinosis, and perennial allergic rhinitis caused by mite and house dust.It is usually used in the treatment of allergic rhinitis. 
 
Usage 
Your dosing schedule prescribed by your doctor is ((        to be written by a healthcare professional)) 
In general, for adults and children aged 12 years and older, take 2 tablets at a time, twice daily, in the morning and evening, on an empty stomach. Strictly follow the instructions. 
Never chew or crush the tablet since this medicine contains controlled-release layer. Swallow with water as it is. 
Because this controlled-release layer is hard to melt, it may be excreted in the feces as a tablet after active ingredient release. 
If you miss a dose, take a dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and follow your regular dosing schedule. You should never take two doses at one time. 
If you accidentally take more than your prescribed dose, consult with your doctor or pharmacist. 
Do not stop taking this medicine unless your doctor instructs you to do so. 
 
Internal capacity 
100  Tablets 
 
＜Warning＞ 
The most commonly reported adverse reactions include headache, rash, fatigue, dry mouth, angioedema, itching, hives, and flushing. If any of these symptoms occur, consult with your doctor or pharmacist. 
  
The symptoms described below are rarely seen as initial symptoms of the adverse reactions indicated in brackets. If any of these symptoms occur, stop taking this medicine and see your doctor immediately. 
  
breathing difficulty, blood pressure decreased, loss of consciousness, angioedema, chest pain, flushing[shock, anaphylaxis] 
paroxysmal muscle contraction[convulsion] 
general malaise, loss of appetite, yellowing in skin and white of eyes[hepatic dysfunction, jaundice] 
throat pain, headache, muscle pain, high fever with chilliness and shivering[agranulocytosis, leucopenia, neutropenia] 
fever, erythema, many small pustule[acute generalized exanthematous pustulosis] 
The above symptoms do not describe all the adverse reactions to this medicine. Consult with your doctor or pharmacist if you notice any symptoms of concern other than those listed above. 
 
Ingredients  
(in 1 tablet)
JP fexofenadine hydrochloride 30mg
Pseudoephedrine hydrochloride 60mg
 
Additives: Carnauba wax, stearic acid, light silicic anhydride, crystalline cellulose, croscarmellose sodium, partially pregelatinized starch, magnesium stearate, polyvinyl alcohol (partially saponified), titanium oxide, macrogol 4000, talc, yellow sesquioxide iron, iron sesquioxide
 
●Dosage form：pale orange tablet, diameter: 17.5 mm, minor axis: 7.8 mm